SINGH , S and GOGOI , B K and BEZBARUAH , R L (2011) Racemic Resolution of some dl-Amino Acids using Aspergillus fumigatusl-Amino Acid Oxidase. Current Microbiology, 63. pp. 94-99.

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Abstract

The ability of Aspergillus fumigatus L-amino acid oxidase (L-aao) to cause the resolution of racemic mixtures of DL-amino acids was investigated with DL-alanine, DL-phenylalanine, DL-tyrosine, and DL-aspartic acid.A chiralcolumn,Crownpak CR?wasusedfortheanalysisof the amino acids. The enzyme was able to cause the resolution of the three DL-amino acids resulting in the production of optically pure D-alanine (100% resolution), D-phenylalanine (80.2%), and D-tyrosine (84.1%), respectively. The optically pure D-amino acids have many uses and thus can be exploited industrially. This is the first report of the use of A. fumigatus L-amino acid oxidase for racemic resolution of DL-amino acids.

Item Type:	Article
Subjects:	Biology > Biotechnology
Divisions:	UNSPECIFIED
Depositing User:	Dr. PK Barooah
Date Deposited:	28 Dec 2011 05:37
Last Modified:	28 Dec 2011 05:37
URI:	http://neist.csircentral.net/id/eprint/119

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