Saikia, P P and BAISHYA, G and Goswami, A and Barua, N C (2008) An efficient reduction protocol for the synthesis of beta-hydroxycarbamates from beta-nitro alcohols in one pot : a facile synthesis of (-)-beta-conhydrine. Tetrahedrom Letters, 49. pp. 6508-6511.

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Abstract

An efficient and practical one-pot protocol for the reduction of b-nitro alcohols to their corresponding N-(tert-butoxycarbonyl) amino alcohols using Zn 13NH4Cl in aqueous methanol is described. Other reducible groups such as ketones and isolated double bonds remained intact. This methodology allows a short synthesis of (�)-b-conhydrine to be achieved.

Item Type: Article
Subjects: Chemistry > Organic Chemistry
Divisions: UNSPECIFIED
Depositing User: Dr. PK Barooah
Date Deposited: 28 Dec 2011 09:01
Last Modified: 28 Dec 2011 09:01
URI: http://neist.csircentral.net/id/eprint/146

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