Saikia, P P and BAISHYA, G and Goswami, A and Barua, N C
(2008)
An efficient reduction protocol for the synthesis of beta-hydroxycarbamates from beta-nitro alcohols in one pot : a facile synthesis of (-)-beta-conhydrine.
Tetrahedrom Letters, 49.
pp. 6508-6511.
Abstract
An efficient and practical one-pot protocol for the reduction of b-nitro alcohols to their corresponding
N-(tert-butoxycarbonyl) amino alcohols using Zn 13NH4Cl in aqueous methanol is described. Other
reducible groups such as ketones and isolated double bonds remained intact. This methodology allows
a short synthesis of (�)-b-conhydrine to be achieved.
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