SARMA , R and BORAH , K J and DOMMARAJU , Y and PRAJAPATI , D
(2011)
Unexpected deviation from diene behaviour of uracil amidine: Towards synthesis of some pyrido[2,3-d]pyrimidine derivatives.
Molecular Diversity,, 15 (3).
pp. 697-705.
Abstract
Condensation products obtained from the treatment
of uracil amidine with preformed or in situ generated
suitably substituted olefins unexpectedly undergo intramolecular
cyclisation during silica gel chromatography to generate
pyrido[2,3-d]pyrimidines. Various reaction conditions
arestudiedandthealterednatureoftheuracilamidinemoleculeisfurtherexploredbyreactingitwithdifferentsuitably
substituted alkenes
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