Das, Saikat Das and Konwar, D (2009) A Simple and Practical Method for the Oxidation of Thebaine to 14-Hydroxycodeinone by V2O5–H2O2. Synthesis (7). pp. 1061-1064.

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Abstract

An efficient, practical and expeditious method has been developed for the oxidation of thebaine to 14-hydroxycodeinone in excellent yield by employing 20 mol% of V2O5 in the presence of 30% H2O2 in aqueous medium. The method provides a clean technological process for the preparation of a key drug intermediate, 14- hydroxycodeinone.

Item Type:	Article
Subjects:	Chemistry > Organic Chemistry
Divisions:	UNSPECIFIED
Depositing User:	Dr. PK Barooah
Date Deposited:	28 Dec 2011 11:17
Last Modified:	28 Dec 2011 11:17
URI:	http://neist.csircentral.net/id/eprint/169

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