Bordoloi, P K and Bhuyan , P D and Baruah, P and Bordoloi, M J and Rao, P G
A long chain alkylated ;1-methylene-;3-butyrolactone from Artabotrys odoratissimus fruit.
Phytochemistry Letters, 2 (1).
pp. 21-24.
Abstract
As part of our ongoing programme for isolation of bioactive molecules
from the flora of the Indo-Burma biodiversity belt, an unusual long chain
alkylated �-methylene-�-butyrolactone was isolated from the juice of
ripe fruit of Artabotrys odoratissimus R.Br. Its structure was determined
as 3-methylene-4-pentadecyldihydrofuran-2-one by spectroscopic
methods. It was found to have good antifungal activity against Alternaria tenuissima Kunze Ex Pers. isolated from solasodine producing plant Solanum khasianum Clarke. Minimum Inhibitory Concentration (MIC)and IC50 for 3-methylene-4-pentadecyldihydrofuran-2-one were found
as 300 and 51.37 ;Cg/ml, respectively. The standard captan was found
to have an MIC and IC50 of 200 and 35.52 ;Cg/ml, respectively
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