Borthakur, M and Barthakur, M G and Boruah, R C (2008) Microwave promoted one-pot synthesis of novel A-ring fused steroidal dehydropiperazines. Steroids, 73 (5). pp. 539-542.

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The preparation of ring-A fused steroidal dehydropiperazine at the 3,4-position is herein described. The novel steroidal dehydropiperazines were prepared from the annulation reaction of ethylenediamine with 3-keto-4-en steroids in a one-pot reaction under microwave irradiation. The key step involves base catalysed aerial oxidation of the C-6 methylene group followed by cyclocondensation of ethylenediamine via Michael addition reaction.

Item Type: Article
Subjects: Chemistry > Organic Chemistry
Depositing User: Dr. PK Barooah
Date Deposited: 28 Dec 2011 05:50
Last Modified: 28 Dec 2011 05:50

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