BORUAH , M and KONWAR, D and SHARMA, S D (2007) KF/Al2O3 mediated 1,3-dipolar cycloaddition of azomethine ylides: a novel and convenient procedure for the synthesis of highly substituted pyrrolidines. Tetrahedron Letters, 48 (26). pp. 4535-4537.

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Abstract

—The regio- and diastereoselective synthesis of pyrrolidine derivatives through 1,3-dipolar cycloaddition of an azomethine ylide and dipolarophile mediated by KF/Al 2O 3, a versatile solid supported reagent, is reported. KF/Al 2O 3 is sufficiently basic such thatitcandeprotonatea-iminoesterstogenerateazomethineylidesanditalsofunctionsasasolidsupportedcatalystleadingtothe cycloadduct rather than the Michael adduct.  2007 Elsevier Ltd. All rights reserved.

Item Type:	Article
Subjects:	Chemistry > Organic Chemistry
Divisions:	UNSPECIFIED
Depositing User:	Dr. PK Barooah
Date Deposited:	30 Dec 2011 09:30
Last Modified:	30 Dec 2011 09:30
URI:	http://neist.csircentral.net/id/eprint/250

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