Das , Sharma S and Hazarika, P and Konwar, D
(2008)
A simple, green and one-pot four-component synthesis of 1,4-dihydropyridines and their aromatization.
Catalysis Communications, 9 (5).
pp. 709-714.
Abstract
A simple, green and cost-effective protocol was achieved for the solvent free synthesis of 1,4-dihydropyridines catalyzed by
AlCl3 Æ 6H2O as a mild and effective catalyst at 60 �C in high yields. 1,4-Dihydropyridines thus formed were aromatized to pyridines
by in situ generation of HOCl employing AlCl3 Æ 6H2O/H2O2/H2O/EtOH as an excellent reagent system under domestic microwave irradiation
(MWI). Both the synthesis and oxidation steps were efficiently accomplished in one-pot four-component fashion following the
same protocol
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