THAKUR , D and YADAV , A and GOGOI , B K and BORA , T C
(2007)
Isolation and screening of Streptomyces in soil of protected forest areas from the states of Assam and Tripura, India, for antimicribial metabolites.
Journal de Mycologie Medicale, 17 (4).
pp. 242-249.
Abstract
Objective. — To study the antimicrobial of Antinomycets, isolated from Northeast India.
Material and methods. — A total of 110 actinomycetes strains were isolated from the soil
samples collected from the protected forest soil from two States in Northeast India These were
then characterized by conventional methods and assessed for their antagonistic activity preliminary
against test microorganisms.
Results. — Amongthe110isolates,65(59.09%)strainsshowedantibacterialactivity,47(42.72%)
strains showed antifungal activity and 33 (30%) strains exhibited a broad-spectrum activity
against both test bacteria and fungi. The production of nonpolyenic antifungal substances by
promising isolates was investigated using several criteria: antibacterial activity, ergosterol
inhibition, and UV—vis spectra of active extracts.
Conclusion. — These results indicate that the protected areas of Northeast India’s soil microorganisms
could be an interesting source of antibacterial and antifungal bioactive substances.
# 2007 Elsevier Masson SAS. All rights reserved.
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